Nickel, Cobalt and Palladium Catalysed C-H Functionalization of Un-Activated C(sp3)-H Bond

This review represents nickel, cobalt and palladium catalyzed C-H activation of sp(3) carbon, with special emphasis on methyl C-H activation. The importance of directing group assistance and effect of ligand on beta- or gamma- C(sp(3))-H activation is summarized in this review. The mechanistic study for Ni, Co and Pd catalyzed sp(3) C-H bond functionalization also discussed in detail.