期刊
CHEMICAL RECORD
卷 14, 期 3, 页码 482-491出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201402016
关键词
fluorine; transition metals; catalysis; radiotracer synthesis
资金
- NSF [CHE-0952753]
- NIH-NIGMS [GM088237]
- NIH-NIBIB [EB013042]
- AFOSR [FA9550-10-1-0170]
- DOE SCGF
In this account, we review work from our lab on the development of methods for carbon-fluorine bond formation, with an emphasis on late-stage fluorination of functionalized small molecules and synthesis of 18F-labeled molecules for potential use as tracers in positron emission tomography (PET). We attempt to highlight reactions that we feel are of particular practical relevance, as well as areas of research where there is still significant room for advancement.
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