Predictors of Satisfactory Surgical Outcome in Idiopathic Normal Pressure Hydrocephalus (Review)

Idiopathic normal pressure hydrocephalus is a widespread neurodegenerative disease of the elderly. If not treated surgically early, it results in a severe decrease in quality of life and disability. According to current clinical Russian and foreign guidelines the candidates for CSF shunting procedures are selected based on the results of invasive tests, though treatment outcomes are not always optimal. At the same time, in the last decade there have been published a number of studies on promising noninvasive diagnosis and prognosis of the surgical treatment of idiopathic normal pressure hydrocephalus based on neuroimaging findings. The aim of the present systematic review is to demonstrate the most promising imaging predictors of satisfactory outcomes of CSF shunting procedures in patients with idiopathic normal pressure hydrocephalus based on published literature data.

Automated summary

Idiopathic normal pressure hydrocephalus is a common neurodegenerative disease in the elderly, which will seriously affect the quality of life and lead to disability if not treated surgically in time. Current clinical guidelines select surgical candidates based on the results of invasive tests, but the treatment effect is not ideal. In recent years, some progress has been made in non-invasive diagnosis and prognosis research based on neuroimaging. The purpose of this systematic review is to demonstrate the promising imaging predictors of satisfactory results of CSF shunting procedures in patients with idiopathic normal pressure hydrocephalus.