期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 79, 页码 11108-11111出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc05362f
关键词
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资金
- BBSRC [BB/M025624/1] Funding Source: UKRI
We describe an ultrasensitive electrochemical genosensor based on gold nanoparticles and cobalt-porphyrin functionalised ssDNA probes. The sensitivity at the attomolar concentration level arises from an increased density of redox labels on the electrode surface compared to sensors without NP modification. The electrode detects as few as 23 DNA molecules, approaching single molecule detection.
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