期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 72, 页码 10160-10163出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc05178j
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资金
- EPSRC [EP/M005062/1, EP/K039547/1]
- Leverhulme Trust [RF-2013-286]
- University of Manchester
- EPSRC [EP/K039547/1, EP/P001386/1] Funding Source: UKRI
Amidines bearing simple alkenes undergo aminal radical cyclisation upon treatment with SmI2. The mild, reductive electron transfer process delivers medicinally-relevant, polycyclic quinazolinone derivatives in good to excellent yield and typically with complete diastereocontrol.
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