期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 72, 页码 10176-10178出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc04007a
关键词
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资金
- Cancer Research UK Cambridge Centre Pump Prime Research Grant
- ERASMUS placement organisation
- DAAD
- EPSRC-CRUK Cancer Imaging Centre in Cambridge and Manchester [C197/A16465]
- CRUK [C14303/A17197, C47594/A16267]
- EU [FP7-PEOPLE-2013-CIG-630729]
- University of Zaragoza [UZ2018-CIE-04]
- ARAID
We report an active DNA construct capable of probing pH through a photoacoustic (PA) ratiometric analysis approach. Our nanoprobe enables different PA readout in tissue mimicking phantoms in the range between pH 6.8 to 7.8 at physiologically relevant sodium concentrations. Thus, it represents a promising platform to probe pH values relevant to the tumor microenvironment using PA.
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