期刊
CHEMICAL COMMUNICATIONS
卷 54, 期 67, 页码 9309-9312出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc05687k
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资金
- CSIR Mission Mode Project on Nano-biosensors and Microfluidics for Healthcare
- UGC, India
- ICMR, India
- CSIR, India
A matrix metalloproteinase (MMP) targeted tetrapeptide vesicle has been designed and developed, which strongly binds at a MMP9 enzymatic site. Interestingly, it has a propensity to encapsulate and deliver the doxorubicin drug specifically to the cancer cell, induces superior apoptotic death, and inhibits the metastatic cancer cell migration and growth of multicellular 3D spheroids.
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