期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 78, 页码 11550-11553出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03731f
关键词
-
资金
- [K25AG036760]
- [K99AG042026]
In this report, we designed a highly bright bifunctional curcumin analogue CRANAD-28. In vivo two-photon imaging suggested that CRANAD-28 could penetrate the blood brain barrier (BBB) and label plaques and cerebral amyloid angiopathies (CAAs). We also demonstrated that this imaging probe could inhibit the crosslinking of amyloid beta induced either by copper or by natural conditions.
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