4.7 Article

Phosphine-catalyzed sequential annulation domino reaction: rapid construction of bicyclo[4.1.0]heptene skeletons

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 43, 页码 5710-5713

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01097c

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  1. National Natural Science Foundation of China [21172115]
  2. Research Fund for the Doctoral Program of Higher Education of China [20120031110002]

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A convenient and efficient phosphine-catalyzed sequential annulation domino reaction between dienic sulfones and MBH carbonates has been developed. In the presence of 20 mol% of tris(4-fluorophenyl)phosphine, functionalized bicyclo[4.1.0]heptenes were prepared in excellent yields and stereoselectivities under mild conditions.

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