4.7 Article

Palladium/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 67, 页码 9550-9553

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03920c

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资金

  1. National Science Foundation of China [21272087, 21202053, 21232003]
  2. National Basic Research Program of China [2011CB808603]

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The Pd/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination with a wide range of O- and N-nucleophiles have been developed (up to 97% yield, 985% ee). The products can also be conveniently transformed into biologically active chiral heterocycles.

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