期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 31, 页码 4096-4098出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49198f
关键词
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资金
- Estonian Ministry of Education and Sciences [SF0180121s08]
- Estonian Science Foundation [8230, 8419, ERMOS30]
- Estonian Research Council [IUT20-17]
- SGC [1097737]
- Danish Cancer Society [DP07109]
Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to sensitive responsive photoluminescent probes for protein kinase CK2 that emitted red light with a long (microsecond-scale) decay time upon excitation of the probes with a pulse of near-UV light.
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