4.7 Article

Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 75, 页码 10945-10948

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05215c

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资金

  1. National Natural Science Foundation of China [21172274, 21231007, 21121061, 21201183, J1103305]
  2. State High-Tech Development Program (863 Program) [2012AA020305]
  3. Ministry of Education of China [20100171110013, 313058]
  4. National Basic Research Program of China (973 Program) [2014CB845604]
  5. Fundamental Research Funds for the Central Universities

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The successful design and anticancer mechanistic studies of a series of cyclometalated Ir(III) complexes with histone deacetylase inhibitory and photodynamic therapy (PDT) activities are reported.

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