4.7 Article

pH-Triggered Au-fluorescent mesoporous silica nanoparticles for 19F MR/fluorescent multimodal cancer cellular imaging

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 3, 页码 283-285

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47324d

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资金

  1. Natural Science Foundation of China [81227902, 21221064, 21120102038, 11004228, 21305156]
  2. Innovation Method Fund of China [2010IM030600]
  3. Chinese Academy of Sciences [KJCX2-EW-N06-04]

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Novel pH-triggered nanoprobe were fabricated for F-19 MRI and fluorescence imaging (MRI-FI) of cancer cells. The biocompatibility, durability, high internalizing efficiency and pore architecture justify the Au-fluorescent mesoporous silica nanoparticles as ideal, highly sensitive and highly specific vectors for F-19 MRI and FI of cancer cells.

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