期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 63, 页码 8628-8639出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02290d
关键词
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资金
- NIH (NIGMS) [R01-GM079554]
- Welch Foundation [I-1596]
- UT Southwestern
The pyrrole-imidazole alkaloids are a group of structurally unique and biologically interesting, marine sponge metabolites. Among them, the cyclic dimers have caught synthetic chemists' attention particularly. Numerous synthetic strategies have been developed and various biosynthetic hypotheses have been proposed for these fascinating natural products. We discuss herein the synthetic approaches and the biosynthetic insights obtained from these studies.
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