期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 29, 页码 3789-3791出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00016a
关键词
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资金
- National Natural Science Foundation of China [51273037, 50903012, 21174142]
- Jilin Science and Technology Bureau [20130206074GX]
- Jilin Human Resources and Social Security Bureau [201125020]
- International Cooperation Project [20120729]
Supramolecular nanogels cross-linked by host-guest interaction between dextran grafted benzimidazole (Dex-g-BM) and thiol-beta-cyclodextrin were designed. Their special supramolecular pH-sensitivity under acidic conditions (pH < 6, within the range of malignant cellular endosomes) and reduction sensitivity in response to biologically relevant stimuli will be of great advantage to the future of cancer chemotherapeutics.
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