期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 53, 页码 6987-6990出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02119c
关键词
-
资金
- Natural Science Foundation of China [30973619, 81172931]
- National High-tech RD 863 Program [2008AA02Z304]
A simple and novel furanyl acryl conjugated coumarin fluorophore was designed as an effective thioredoxin reductase (TrxR)-responding fluorescent probe by an activity-guided approach. Basically, the alpha,beta-unsaturated ketone moiety in the probe structure could quench the fluorescence of the coumarin, but upon the covalent modification of TrxR, a significant fluorescence could be generated, which has been confirmed to be obviously selective over Trx, GSH, Cys and DTT.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据