期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 89, 页码 13789-13792出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc06577h
关键词
-
资金
- Caltech-City of Hope Biomedical Research Initiative
- Caltech Summer Undergraduate Research Fellowship program
We have synthesized and characterized a water-soluble gold(III) corrole (1-Au) that is highly toxic to cisplatin-resistant cancer cells. Relative to its 1-Ga analogue, axial ligands bind only weakly to 1-Au, which likely accounts for its lower affinity for human serum albumin (HSA). We suggest that the cytotoxicity of 1-Au may be related to this lower HSA affinity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据