4.7 Article

Catalytic activity of a dual-hemin labelled oligonucleotide: conformational dependence and fluorescent DNA sensing

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CHEMICAL COMMUNICATIONS
卷 50, 期 97, 页码 15362-15365

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc07298g

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资金

  1. National Basic Research Program of China [2010CB732400]
  2. National Natural Science Foundation of China [21135002, 21121091, 21475063]
  3. Leading Medical Talents Program from the Department of Health of Jiangsu Province
  4. Science Foundation of Jiangsu [BL2013036]

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The conformation-dependent peroxidase activity of a dual-hemin labelled oligonucleotide was identified and conveniently utilized to design a sensitive homogenous fluorescent method for DNA sensing.

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