4.7 Article

Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 73, 页码 10661-10664

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05307a

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资金

  1. National Science Foundation [CHE-1152488]
  2. National Institutes of Health [NIGMS 104349]
  3. China Scholarship Council [2012061915013]
  4. Direct For Mathematical & Physical Scien
  5. Division Of Chemistry [1152488] Funding Source: National Science Foundation

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An efficient room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl bromides is presented. The Pd(OAc)(2)/NiXantphos-based catalyst enables the introduction of various aryl and heteroaryl groups, via a deprotonative cross-coupling process (DCCP) in good to excellent yields (60-99%).

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