期刊
CHEMICAL COMMUNICATIONS
卷 50, 期 38, 页码 4904-4907出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00967c
关键词
-
资金
- National Institute for Drug Abuse [DP1 DA031387]
Combining computer-assisted drug design and synthetic efforts, we generated compounds with potent and balanced activities toward both D3 dopamine receptor and fatty acid amide hydrolase (FAAH) enzyme. By concurrently modulating these targets, our compounds hold great potential toward exerting a disease-modifying effect on nicotine addiction and other forms of compulsive behavior.
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