4.7 Article

A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 14, 页码 1751-1753

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48128j

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资金

  1. China Scholarship Council (CSC)
  2. University of Bath Full Fees Scholarship
  3. Oriental Scholarship
  4. Fundamental Research Funds for the Central Universities [WK1013002]
  5. Royal Society

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A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF-ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.

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