4.7 Article

Sensitive and selective amplified visual detection of cytokines based on exonuclease III-aided target recycling

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 87, 页码 13342-13345

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc05701e

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资金

  1. Social Development Fund of Jiangsu Province [BE2013614]
  2. Grants from National Natural Science Foundation [81300787]
  3. Natural Science Foundation of Jiangsu Province [BK2011168, BK2012105, BK20041103]
  4. Technology Infrastructure Plan of Jiangsu Province-Technology Public Service Platform [BM2012066]
  5. Youth Foundation of Jiangsu Institute of Nuclear Medicine

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A new Exo III assisted strand-cleavage cycle and ligand-responsive quadruplex formation strategy for amplified and label-free detection of IFN-gamma was reported with a detection limit of 0.1 pM and a visual detection limit of 20 pM by the naked eye.

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