4.7 Article

Detection of cancer cells using triplex DNA molecular beacons based on expression of enhanced green fluorescent protein (eGFP)

期刊

CHEMICAL COMMUNICATIONS
卷 50, 期 67, 页码 9547-9549

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03925d

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资金

  1. National Science Foundation of China [21275086, 21227008]
  2. Promotive Research Fund for Excellent Young and Middle-aged Scientists of Shandong Province [BS2011SW001]
  3. Open Project of State Key Laboratory of Crop Biology [2011KF10]
  4. Postdoctoral Foundation of Qingdao University of Science and Technology [400-0022607]

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A novel strategy was proposed for Ramos cell detection by combining the expression of enhanced green fluorescent protein (eGFP) with the cell aptamer recognition and the triplex molecular beacons. This system was successfully applied to cancer cell detection with high sensitivity and specificity.

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