A trinuclear Zn3(OAc)4-3,3′-bis(aminoimino)-binaphthoxide complex for highly efficient catalytic asymmetric iodolactonization

A 3,3'-bis(aminoimino)BINOL ligand was newly designed and synthesized for the formation of a trinuclear Zn complex upon reaction with Zn(0Ac)2. Using the harmony of the tri-zinc atoms, 1 mol% Zn3(0Ac)4-3,3'-bis(aminoimino)binaphthoxide catalyzed asymmetric iodolactonization in up to 99.9% ee.