Porous platinum nanotubes modified with dendrimers as nanocarriers and electrocatalysts for sensitive electrochemical aptasensors based on enzymatic signal amplification

A highly sensitive electrochemical aptasensor for thrombin detection is developed and demonstrated by using porous platinum nanotubes modified with polyamidoamine dendrimers as nanocarriers and electrocatalysts. The proposed strategy affords a low detection limit of 0.03 pM based on enzyme-based signal amplification.