期刊
CHEMICAL COMMUNICATIONS
卷 49, 期 12, 页码 1184-1186出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc38659c
关键词
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资金
- Spanish Ministry of Science and Innovation (MICINN) [AYA2009-13920-C02-02]
- MICINN
- University of Bologna
- University of Southampton
- Medical University of Lodz [503/1-156-02/503-01]
All in one pot: an organocatalytic highly enantioselective synthesis of alpha-methylene-gamma-lactones has been reported. The reaction between protected 2-hydroxymalonates and MBH carbonates is simply catalysed by chiral Lewis bases affording after acid treatment the corresponding lactones in excellent yields and enantioselectivities.
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