4.7 Article

Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C-H functionalization of alcohols

期刊

CHEMICAL COMMUNICATIONS
卷 49, 期 68, 页码 7540-7542

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc44055a

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资金

  1. National Natural Science Foundation of China [21102111, 21102110]
  2. Fundamental Research Funds of the Central Universities

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A metal-free tandem radical addition/cyclization reaction of activated alkenes and alcohols has been developed. The process provides an efficient and atom economical access to various valuable hydroxylcontaining oxindoles through the direct sp(3) C-H functionalization of alcohols.

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