Supramolecular hydrogels based on bola-amphiphilic glycolipids showing color change in response to glycosidases

We developed supramolecular hydrogels exhibiting reversible thermochromism concurrently with gel-to-sol transition from four glycolipids. In addition, these gels showed the similar color change in response to glycosidases, which can be employed to construct a colorimetric sensor array chip for sensing glycosidases with the naked eye.