期刊
CHEMICAL COMMUNICATIONS
卷 49, 期 26, 页码 2625-2627出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc38674k
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资金
- Principado de Asturias
- Spanish MICINN
- MICINN [MICINN-12-CTQ2011-24237]
- BIOTRAINS Marie Curie ITN
- European Union through the Seventh Framework People Programme [238531]
A fully convergent one-pot two-step synthesis of different chiral 1,2,3-triazole-derived diols in high yields and excellent enantio-and diastereoselectivities has been achieved under very mild conditions in aqueous medium by combining a single alcohol dehydrogenase (ADH) with a Cu-catalysed 'click' reaction.
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