Fluorescent detection of cholesterol using beta-cyclodextrin functionalized graphene

A fluorescence based cholesterol detection method has been developed using competitive host-guest interaction between graphene bound beta-cyclodextrin (beta-CD) with rhodamine 6G (R6G) and cholesterol. Fluorescence of beta-CD incorporated R6G is quenched by graphene but is 'turned on' by cholesterol as it replaces R6G from the beta-CD host.