期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 50, 页码 6274-6276出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31641b
关键词
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资金
- National Basic Research Program of China [2012CB910601]
- National Natural Science Foundation [20935004, 20875085]
- Creative Research Group by NSFC [21021004]
- MOST [20102010IM030500]
- National Key Technology RD Program [2008BAK41B02, 2009BAK59B02]
A new type of IMAC material, with ATP as the chelating ligand, was synthesized and applied to capture phosphopeptides. For the first time, the approach for phosphopeptide enrichment could provide selectivity under 5000-fold dilution by nonphosphopeptides, and sensitivity of on-target enrichment at 3 amol.
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