期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 77, 页码 9649-9651出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33359g
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资金
- American Cancer Society [IRG-85-001-22]
Incorporation of biquinoline ligands into Ru(II) polypyridyl complexes produces light-activated systems that eject a ligand and photobind DNA after irradiation with visible and near-IR light. Structural analysis shows that distortion facilitates the photochemistry, and gel shift and cytotoxicity studies prove the compounds act as anti-cancer photodynamic therapy (PDT) agents in the tissue penetrant region.
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