期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 44, 页码 5482-5484出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31537h
关键词
-
资金
- Office of Naval Research [N00014-09-1-0848]
- National Institutes of Health [R00RR024366]
A modular system for detecting protease activity via enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
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