期刊
HUMAN & EXPERIMENTAL TOXICOLOGY
卷 19, 期 1, 页码 41-75出版社
SAGE PUBLICATIONS LTD
DOI: 10.1191/096032700678815602
关键词
hormesis; low dose; stimulation; beta-curve; radiation
类别
This paper represents the first systematic effort to describe the historical foundations of radiation hormesis. Spanning the years from 1898 to the early 1940's the paper constructs and assesses the early history of such research and evaluates how advances in related scientific fields affected the course of hermetic related research. The present effort was designed to not only address this gap in current knowledge, but to offer a toxicological basis for how the concept of hormetic dose-response relationships may affect the nature of the bioassay and its role in the risk assessment process.
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