Fluorescent conjugated block copolymer nanoparticles by controlled mixing

Monitoring of the formation of stable fluorescent nanoparticles from controlled mixing of a THF solution of poly(fluorene ethynylene)-block- poly(ethylene glycol) in a microfluidic laminar flow cross-junction by spatially resolved fluorescence spectroscopy reveals the time scale of particle formation as well as incorporation of small molecule guests and the role of solvent mixing.