4.7 Article

Chemiluminescence biosensors for DNA detection using graphene oxide and a horseradish peroxidase-mimicking DNAzyme

期刊

CHEMICAL COMMUNICATIONS
卷 48, 期 8, 页码 1126-1128

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc16868e

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  1. National Key Scientific Program-Nanoscience and Nanotechnology [2006CB933103]
  2. National Science Foundation of China [21075093, 20921062]

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In this communication, we demonstrate that graphene oxide (GO) greatly inhibits the peroxidatic activity of a horseradish peroxidase-mimicking DNAzyme. Combining this observation with the unique DNA/GO interactions, an ultrasensitive GO-based chemiluminescence DNA biosensing platform is developed.

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