4.7 Article

Highly enantioselective Friedel-Crafts alkylation reaction catalyzed by rosin-derived tertiary amine-thiourea: synthesis of modified chromanes with anticancer potency

期刊

CHEMICAL COMMUNICATIONS
卷 48, 期 3, 页码 446-448

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14379d

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资金

  1. National Natural Science Foundation of China [20932003, 90813012]
  2. Ministry of Science and Technology of China [2009ZX09503-017]
  3. Fundamental Research Funds for the Central Universities of China [860618]

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We present herein for the first time the synthesis and preliminary biological evaluation of various modified chromanes via a rosin-derived tertiary amine-thiourea-catalyzed highly enantioselective Friedel-Crafts alkylation reaction.

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