期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 62, 页码 7702-7704出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33576j
关键词
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资金
- Department of Science and Technology, Government of India [SR/S5/MBD-02/2007]
- J.C. Bose fellowship
- UGC
- CSIR (New Delhi)
Curcumin (Hcur) as a cellular imaging and PDT agent shows remarkable photocytotoxicity in HeLa cells in visible light of 400-700 nm giving IC50 = 8.2 +/- 0.2 mu M and its degradation is arrested on formation of photocytotoxic dipyridophenazine (dppz) complex [VO(cur)(dppz)Cl] (IC50 = 3.3 +/- 0.4 mu M), while both are less toxic in the dark.
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