Highly regioselective synthesis of aryl chalcogenides through C-H functionalization of arenes

We report here the regioselective synthesis of aryl chalcogenides through the iridium-catalyzed meta C-H borylation followed by copper-catalyzed C-S coupling reaction with chalcogenide sources in one pot, giving the 3,5-disubstituted aryl chalcogenides with high regioselectivity and good yields.