4.7 Article

Photophysical and biological investigation of novel luminescent Ru(II)-polypyridyl-1,8-naphthalimide Troger's bases as cellular imaging agents

期刊

CHEMICAL COMMUNICATIONS
卷 48, 期 20, 页码 2588-2590

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17274g

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资金

  1. Science Foundation Ireland [SFI RFP 2009, SFI 2010 PI]
  2. HEA PRTLI Cycle 4
  3. The Irish Research Council for Science, Engineering and Technology (IRCSET)
  4. Regione Autonoma della Sardegna

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The synthesis and photophysical properties of 1 and 2, two Ru(II)-polypyridyl based-1,8-naphthalimide Troger's bases, are described; these were found to stabilize double stranded DNA, undergo rapid cellular uptake, displaying good luminescence without affecting cell viability even after 24 hours of incubation.

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