期刊
NEUROLOGICAL SCIENCES
卷 21, 期 5, 页码 S981-S982出版社
SPRINGER-VERLAG
DOI: 10.1007/s100720070015
关键词
MELAS; idebenone; ribonavin; therapy
We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.
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