4.7 Article

Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations

期刊

CHEMICAL COMMUNICATIONS
卷 48, 期 84, 页码 10398-10400

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc35625b

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资金

  1. Japan Science and Technology Corporation (JST)
  2. WPI program (iCeMS, Kyoto University)
  3. Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan
  4. Japan Society for the Promotion of Science (JSPS) for the Postdoctoral fellowship

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We describe asymmetric intramolecular Friedel-Crafts alkylations with a DNA-based hybrid catalyst and propose a plausible binding model. This study shows promise for studying relationships between the helical chirality of DNA and enantioselectivity of the chemical reaction.

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