期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 26, 页码 3224-3226出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17542h
关键词
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A new concept of a chemically deactivatable quencher is proposed for a FRET-based probe that turns-on its fluorescence by either an enzymatic cleavage or a chemical reagent (sodium dithionite). This concept allowed us to quantify the caspase-3 cleavage activity in solution and to reveal unreacted probes in cell experiments.
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