期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 12, 页码 1754-1756出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc16218k
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资金
- Ford Foundation
- R.A. Welch Foundation [A-0673]
- Puerto Rico Louis Stoke Alliance for Minority Participation [HRD-0601843]
- NIH-MARC [5D34GM007821]
- NIH-RISE [R25GM061151]
- Division Of Graduate Education
- Direct For Education and Human Resources [0841338] Funding Source: National Science Foundation
Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin.
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