期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 51, 页码 6357-6359出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31275a
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资金
- Dutch Polymer Institute (DPI, technology area HTE)
Post-polymerization modification of a poly(pentafluorostyryl) backbone with beta-D-galactose and a terpyridine platinum complex yields a well-defined material that represents the first example of a metal-conjugated glycopolymer. It reveals antiproliferative activity, no detectable necrotic cytotoxicity, and efficiently induces apoptosis in both wild-type as well as resistant Nalm-6 leukemia cell lines.
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