期刊
ANTIOXIDANTS & REDOX SIGNALING
卷 2, 期 3, 页码 449-460出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/15230860050192224
关键词
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Aging is accompanied by a decline of functions controlled by the central dopaminergic system, such as reduced locomotor activity, motivation, impairment of memory formation, and learning deficits. The molecular mechanisms underlying age-related impairment of dopaminergic functions are unknown. Current literature and our own recent work, which are reviewed and summarized in the present paper, suggest that dopamine oxidative stress and its subsequent signaling may contribute to the aging of dopaminergic system. Antiox. Redox Signal. 2, 449-460.
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