期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 72, 页码 9053-9055出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34816k
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资金
- Spanish National Research Council (CSIC)
- CONICYT
- Programa Bicentenario Becas-Chile
- [BFU2011-25326]
- [BFU2011-24595]
An efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantio-selectivity in different biotransformations.
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