期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 71, 页码 8958-8960出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32240d
关键词
-
资金
- Australian Research Council (ARC)
- Merit Allocation Scheme of the National Computing Infrastructure at the ANU
Molecular dynamics simulations were used to investigate the binding of four different 2,4,6-triarylpyridines to G-quadruplex DNA. Both the binding free energies, and the kinetics of binding are required to explain the measured degree of ligand induced stabilisation of the compounds, with bulky substituents having the potential to prevent the ligand from reaching the lowest energy binding site.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据