4.7 Article

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

期刊

CHEMICAL COMMUNICATIONS
卷 48, 期 65, 页码 8120-8122

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33214k

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资金

  1. National Natural Science Foundation of China [91027021, 91027041, 51173124, 51172151, 50903059, 50825304]
  2. National Basic Research Program of China (973 Program) [2010CB934500, 2011CB808400]
  3. Specialized Research Fund for the Doctoral Program of Higher Education of China [20093201120020]
  4. Natural Science Foundation of Jiangsu Province [BK2010003]
  5. Priority Academic Program Development of Jiangsu Higher Education Institutions

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We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

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