A chiral metal-organic framework for sequential asymmetric catalysis

A chiral metal-organic framework (MOF) of the lcy topology was constructed from the Mn-Salen derived dicarboxylic acid and the [Zn(4)(mu(4)-O)(O(2)CR)(6)] secondary building unit, and used in highly regio- and stereo-selective sequential alkene epoxidation/epoxide ring-opening reactions.